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Target intelligence / Profile preview
Tripartite motif-containing protein 77 (TRIM77)
- Target
- TRIM77
- Molecular classification
- Other (Predicted E3 ubiquitin ligase, putative/pseudogene; not a receptor, enzyme, channel, or transporter[2][8].), TRIM family (Tripartite motif family; RBCC domain structure[1].)
01
Overview
Tripartite motif-containing protein 77 (TRIM77) is a member of the TRIM family, characterized by an RBCC (RING, B-box, coiled-coil) structural motif, suggesting potential E3 ubiquitin ligase function involved in post-translational modification, regulation of gene expression, and innate immunity, though these functions are predicted rather than confirmed. TRIM77 is often annotated as a pseudogene or a putative protein, with no experimental evidence confirming expression, molecular function, or association with specific diseases. TRIM77 is not recognized as a validated therapeutic target or biological receptor/enzyme in human biology, and current knowledge is extrapolated from general TRIM family roles[1][2][4][8].
- Other names
- TRIM77TRIM77PTripartite motif-containing protein 77Tripartite motif containing 77 pseudogenePutative tripartite motif-containing protein 64DTRIM77-isoform
02
Biological functions
Ubiquitin protein ligase activity (predicted, not experimentally confirmed[2][8].)Regulation of gene expression (predicted[2][4].)Innate immune response (predicted involvement[2][4].)
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