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Target intelligence / Profile preview
tRNA methyltransferase subunit 11-2 pseudogene 3 (TRMT112P3)
- Target
- TRMT112P3
- Molecular classification
- Other (Pseudogene)
01
Overview
tRNA methyltransferase subunit 11-2 pseudogene 3 (TRMT112P3) denotes a region of DNA that closely resembles the functional TRMT112 gene but does not encode a functional protein[3][4]. Pseudogenes are generally nonfunctional and result from duplication or retrotransposition of functional genes; they lack biological activity, are not therapeutic targets, and have no known disease relevance or druggability. Any reference to TRMT112P3 as a target for therapy or biomarker development is incorrect[3][4]. Only the active TRMT112 gene (not TRMT112P3) is involved in protein and RNA methylation, and is associated with some diseases[5][1].
- Other names
- TRMT112P3
02
Mechanism of action
none
03
Biological functions
None (pseudogenes lack biological function)
04
Disease associations
None reported for TRMT112P3; some diseases are associated with the functional TRMT112 gene, but not TRMT112P3
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