tRNA methyltransferase subunit 11-2 pseudogene 4 (TRMT112P4)

tRNA methyltransferase subunit 11-2 pseudogene 4 (TRMT112P4) is classified as a pseudogene, which means it is a non-functional segment of DNA resembling the protein-coding gene TRMT112 (tRNA methyltransferase activator subunit 11-2). Pseudogenes typically arise from duplication or retrotransposition events and acquire disabling mutations so they do not encode active proteins[2]. There is no evidence that TRMT112P4 encodes a protein, is expressed, or plays any known biological or pathogenic role. It is not regarded as a therapeutic target, enzyme, receptor, or any functional biomolecule. The functional gene TRMT112, by contrast, encodes a protein methyltransferase co-factor involved in tRNA and rRNA modification, but TRMT112P4 does not share this activity[1]. Key clarification: There is nothing functionally or therapeutically relevant about TRMT112P4—its designation as a pseudogene means it is not a true molecular target. If you require information on the functional gene (TRMT112), see below: TRMT112 (tRNA methyltransferase activator subunit 11-2): - Molecular classification: Enzyme co-factor (activates methyltransferases) - Biological functions: Catalyzes or enables rRNA and tRNA methylation, protein methylation, histone methylation, and macromolecule metabolism[1]. - Disease roles: Linked to rare syndromes (e.g., Galloway-Mowat, Williams-Beuren)[1]. - Interacting drugs/biomarkers: None specific as a direct drug target[1]. Summary: TRMT112P4 is a non-functional DNA sequence and not a molecular target or therapeutic entity. If your interest is in methyltransferases, you should focus on the functional gene TRMT112 or other related protein-coding genes, not on pseudogene entries like TRMT112P4[1][2].

Other names

TRMT112P4tRNA methyltransferase activator subunit 11-2 pseudogene 4

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