Target intelligence / Profile preview

tRNA pseudouridine synthase-like 1 (PUSL1)

Target
PUSL1
Molecular classification
Enzyme
01

Overview

tRNA pseudouridine synthase-like 1 (PUSL1) is a protein encoded in humans by the PUSL1 gene. It is predicted to function as a pseudouridine synthase, an enzyme responsible for post-transcriptional modification of RNA by catalyzing the isomerization of uridine to pseudouridine in RNA molecules. Its name and sequence suggest similarity to known pseudouridine synthases, but direct biochemical characterization, disease associations, or drug interactions are not documented in the current literature or major protein knowledgebases[6][7].

Other names
PUSL1Pseudouridine synthase-like 1C9orf114
02

Biological functions

Catalyzes pseudouridylation of RNA substrates (predicted)Likely involved in RNA modificationPossible role in RNA stability and processing
03

Disease associations

Other (no disease links described in current sources)

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