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Target intelligence / Profile preview
tRNA splicing endonuclease subunit 15 pseudogene 1 (TSEN15P1)
- Target
- TSEN15P1
- Molecular classification
- Other (Pseudogene)
01
Overview
TSEN15P1 is a pseudogene related to the tRNA splicing endonuclease subunit 15 gene (TSEN15). Unlike TSEN15, which encodes a non-catalytic component of the tRNA splicing endonuclease complex involved in intron removal from precursor tRNAs (a process essential for proper tRNA maturation and brain development), TSEN15P1 itself does not encode a functional protein and is not known to have direct biological functions or disease associations. Functional and disease relevance in the literature pertains solely to TSEN15, where mutations cause pontocerebellar hypoplasia and neurodevelopmental disorders. TSEN15P1 does not have established protein interactions, drug associations, or clinical utility as a biomarker or therapeutic target.
02
Mechanism of action
None reported
03
Biological functions
None for TSEN15P1 specifically (As a pseudogene, it does not have direct biological functions)
04
Disease associations
None established for TSEN15P1 itself (Disease associations are with mutations in TSEN15, the active gene, not the pseudogene)
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