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Tropomyosin 3 pseudogene 1 (TPM3P1)

Target
TPM3P1
Molecular classification
Other (pseudogene)
01

Overview

Tropomyosin 3 pseudogene 1 (TPM3P1) is a human pseudogene related to the TPM3 gene, which encodes the slow muscle alpha-tropomyosin protein involved in actin filament stabilization and muscle contraction regulation[1][6]. Pseudogenes like TPM3P1 do not encode functional proteins and generally lack biological or therapeutic relevance, although some pseudogenes may influence gene expression or disease via non-coding RNA effects[2][5][8]. No concrete evidence currently attributes such a function to TPM3P1. Unlike its parent gene TPM3, which is associated with congenital myopathies and has been implicated in certain cancers[4], TPM3P1 itself is neither a recognized drug target nor a biomarker, and no specific diseases or drugs are linked to it[2]. Therefore, for drug discovery or clinical utility, TPM3P1 is not considered an actionable molecular entity. If your intent was to inquire about TPM3 itself, please clarify, as TPM3 is an active protein with roles in muscle and cancer biology and may have relevant therapeutic associations[1][4][7].

Other names
TPM3L2
02

Biological functions

Other (pseudogenes may act via non-coding RNA mechanisms, but TPM3P1 has no documented function as a protein or therapeutic target)
03

Disease associations

Other (no direct reports of disease association for TPM3P1; TPM3 gene mutations are associated with myopathies and cancer, but not the pseudogene)

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