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Troponin C (TnC)

Target: TnC
Molecular classification: Calcium-binding protein

Overview

Troponin C (TnC) is a calcium-binding protein that forms part of the troponin complex, which regulates contraction in striated muscle (cardiac and skeletal muscle). It is essential for translating changes in intracellular calcium concentration into mechanical force during muscle contraction.

Mechanism of action

Modulating cardiac contractility through altering calcium sensitivity

Biological functions

Calcium sensingMuscle contraction regulation

Disease associations

Cardiomyopathy

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