TRPM8 channel associated factor 2 pseudogene 1 (TCAF2P1)

TCAF2P1 (TRPM8 channel associated factor 2 pseudogene 1) is a pseudogene located on chromosome 7. It is characterized as a genomic region similar in sequence to protein-coding genes (specifically TCAF2, an interactor/regulator of the TRPM8 ion channel), but TCAF2P1 itself does not encode a functional protein. No evidence supports its use as a therapeutic target, biomarker, or modulator of cellular function. Function and disease associations described for TCAF2 or related proteins are not applicable to TCAF2P1. TCAF2P1 is often confused with TCAF2, which does encode a protein partner/regulator of the TRPM8 channel. TCAF2 modulates TRPM8 and has roles in cell migration and potentially prostate cancer. However, these properties do not extend to TCAF2P1, which is a pseudogene. The presence of "pseudogene" in its name and multiple gene databases confirms that TCAF2P1 is non-coding and does not participate in protein-level or signaling biology. No drugs, safety concerns, mechanisms of action, or disease roles are associated with TCAF2P1. TRPM8 channel associated factor 2 pseudogene 1 (TCAF2P1) is a non-coding pseudogene, not a therapeutic target, and should not be considered for target-based drug discovery or functional studies. All relevant functional and disease data pertain to its protein-coding paralog, TCAF2.

Other names

FLJ40722-likeTCAF2BP