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Target intelligence / Profile preview
Trypsin-2
- Molecular classification
- Enzyme, Serine protease
01
Overview
Trypsin-2 is a serine protease enzyme that plays a central role in protein digestion within the small intestine. It is synthesized as an inactive precursor called anionic trypsinogen and activated by enteropeptidase. Beyond digestion, it may play roles in innate immunity.
- Other names
- Anionic trypsinTrypsin IISerine protease 2Anionic trypsinogenPRSSII
02
Mechanism of action
Hydrolyzes peptide bonds at the carboxyl side of lysine or arginine residues
03
Biological functions
Protein digestionHydrolysis of peptide bondsActivation of digestive proenzymesInnate immunityProdefensin convertase
04
Disease associations
PancreatitisPancreatic injuryPancreatic disease
05
Safety considerations
Alterations or dysregulation can lead to pancreatitis
06
Biomarkers
Elevated levels may indicate pancreatic injury or disease
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