Target intelligence / Profile preview

TSPAN18 antisense RNA 1 (TSPAN18-AS1)

Target
TSPAN18-AS1
Molecular classification
Long non-coding RNA (lncRNA), Antisense RNA, Non-coding RNA
01

Overview

TSPAN18 antisense RNA 1 (TSPAN18-AS1) is a long non-coding RNA (lncRNA) located at chromosome 11p11.2 and is transcribed in the antisense direction relative to the protein-coding tetraspanin gene TSPAN18[3][4]. As an antisense RNA, its primary biological function is believed to be regulation of gene expression, most likely at the transcriptional or post-transcriptional level via base pairing or chromatin modification mechanisms typical of antisense RNAs[2][3]. There is currently no evidence to suggest that TSPAN18-AS1 is itself a receptor, enzyme, transporter, or classical drug target, nor are there drugs known to directly interact with it. Due to the general roles of antisense lncRNAs, TSPAN18-AS1 may participate in fine-tuning expression of the TSPAN18 gene, but specific functional, pathological, or therapeutic relevance has not yet been demonstrated in the literature[2][3][4].

Other names
TSPAN18-AS1TSPAN18 AS1
02

Biological functions

Regulation of gene expression (by antisense mechanisms)Epigenetic regulation (implied by antisense RNA general roles)
03

Disease associations

Other (No specific disease roles or clinical relevance have been clearly described for TSPAN18-AS1 in current literature)

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