Target intelligence / Profile preview

TUBA1B antisense RNA 1 (TUBA1B-AS1)

Target: TUBA1B-AS1
Molecular classification: Other (long non-coding RNA; lncRNA)

Overview

TUBA1B antisense RNA 1 (TUBA1B-AS1) is a **long non-coding RNA (lncRNA)** gene located on chromosome 12 and does not encode a protein[1][3][5][7]. It is transcribed antisense to the TUBA1B gene, and its transcript is classified as an lncRNA. While some lncRNAs regulate gene expression through chromatin remodeling, transcriptional interference, or mRNA stability, the specific biological roles and mechanisms of TUBA1B-AS1 have not been conclusively characterized in current literature. Some gene expression databases link TUBA1B-AS1 to differential expression in various cancers, suggesting it may have a role in human disease, especially hepatocellular carcinoma, but it is neither a classic receptor nor considered a validated therapeutic target to date[3][1].

Other names: RP11-386G11.10

Biological functions

Regulation of gene expression (likely through antisense RNA mechanisms)Putatively acts in regulatory RNA pathways affecting transcriptional or epigenetic processes[3][7]

Disease associations

Cancer (reported association with hepatocellular carcinoma and differentially expressed in various cancer types, but functional specificity largely unknown)[3]

Beyond the preview

Go deeper on TUBA1B antisense RNA 1 (TUBA1B-AS1).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on TUBA1B antisense RNA 1 (TUBA1B-AS1).

Explore the full profile