Target intelligence / Profile preview

Tubulin alpha 1b pseudogene

Molecular classification
Other (Pseudogene; not an active enzyme, receptor, or structural cytoskeletal protein)
01

Overview

This entity represents a *pseudogene version* of the **tubulin alpha 1b** gene. Unlike the protein-coding **TUBA1B** gene, which encodes a cytoskeletal protein involved in microtubule function and is studied in the context of cancer immunology and cell cycle regulation[1][3], **tubulin, alpha 1b pseudogene** does not code for a functional protein[3]. Pseudogenes are remnants of genes that have lost their ability to encode proteins due to mutations or truncations and are *not considered therapeutic targets*. Important clarification: - The **functional gene** is **TUBA1B** (*tubulin alpha 1b*), which is a cytoskeletal component involved in microtubule formation, cell division, and is implicated in the prognosis of several cancers[1][3]. - **ENSG00000249729 / LOC100419045** is specifically labeled as a "pseudogene" and does not produce a functional protein[3]. - As a pseudogene, it cannot be targeted by drugs or act as a receptor, enzyme, or transporter. Summary: The "tubulin, alpha 1b pseudogene" (ENSG00000249729) is not a functional nor druggable target; all physiological and disease relevance is tied to the protein-coding **TUBA1B** gene, not to this pseudogene[3].

Other names
LOC100419045tubulin alpha 1b pseudogeneTubulin alpha 1B pseudogene
02

Biological functions

Other (Does not have active biological function; pseudogenes generally lack transcriptional or translational roles in normal biology)
03

Disease associations

Other (No established roles in disease; functional tubulin alpha isozymes, such as TUBA1B, are implicated in cancer, but not this pseudogene[1][3])

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