Tubulin alpha 3f pseudogene (TUBA3FP)

TUBA3FP encodes a pseudogene related to alpha-tubulin, which is a major structural protein in microtubules; however, as a pseudogene, TUBA3FP is *not* translated into a functional protein and does not contribute to microtubule structure or function. Pseudogenes such as TUBA3FP are typically considered non-functional segments of DNA resulting from the duplication or mutation of protein-coding genes. Genomic databases like GeneCards classify TUBA3FP explicitly as a pseudogene with no protein product or known functional role[4][7]. Essential context and distinctions: - TUBA3FP must not be confused with functional tubulin alpha genes (such as TUBA1A, TUBA3C, TUBA3D), which *are* structural proteins involved in cell cytoskeleton, mitosis, and are established therapeutic targets in oncology via agents that target tubulin polymerization (e.g., taxanes, vinca alkaloids)[2][5][6]. - Some sources may list a large number of functional associations for TUBA3FP due to bioinformatic or genomic linkage, but none indicate a direct protein product, function, disease involvement, or druggability[7]. Summary: TUBA3FP is a non-coding pseudogene that does not encode an active protein and is not a therapeutic target[4][7]. Any entry treating TUBA3FP as a conventional drug target, receptor, enzyme, or biomarker would be incorrect according to current genomic and biomedical understanding.

Other names

Tubulin, alpha pseudogeneTubulin alpha-3F pseudogeneTUBA3FPTubulin, alpha 3f pseudogene

None (Not a drug target)