Target intelligence / Profile preview

Tubulin alpha chain-like 3 (TUBAL3)

Target
TUBAL3
Molecular classification
Structural protein, Cytoskeletal protein, Tubulin family member
01

Overview

Tubulin alpha chain-like 3 (TUBAL3) is a predicted protein in humans that belongs to the tubulin superfamily, playing a role as a structural constituent of the cytoskeleton. It is implicated in microtubule organization and participation in the mitotic cell cycle, presumed to function through GTP binding and polymerization into microtubules[1]. While related to key processes such as cell division and intracellular transport attributed broadly to tubulins, TUBAL3 itself has not been characterized as a direct pharmacological target, and its disease associations are currently limited to correlative findings in superficial urinary bladder cancer and Alzheimer's disease[1].

Other names
TUBAL3Tubulin alpha chain-like 3FLJ21665
02

Biological functions

Structural constituent of cytoskeletonMicrotubule cytoskeleton organizationMitotic cell cycleGTP binding
03

Disease associations

Superficial urinary bladder cancerAlzheimer’s diseaseOther (based on prediction and biomolecular parallels to other tubulin isoforms)

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