Tubulin alpha pseudogene 1 (TUBAP1)

Tubulin alpha pseudogene 1 is classified as a *processed pseudogene* related to the family of genes encoding alpha-tubulin, the structural protein subunit of microtubules[1][5]. Unlike protein-coding tubulin alpha genes such as TUBA1A or TUBA1B, TUBAP1 does not generate a functional protein[1][5]. Pseudogenes are typically non-functional segments of DNA that arise from gene duplication or retrotransposition and have lost the ability to encode a protein. There is no evidence that TUBAP1 is involved in microtubule assembly or any known biological process, and it does not act as a drug or therapeutic target. Information about TUBAP1 is sparse in curated genetic and molecular databases, and it should not be confused with active alpha-tubulin genes, which are targets of classic anti-mitotic drugs and implicated in a range of neurological and developmental disorders. Summary of findings: - TUBAP1 is a *pseudogene* and not an active protein or therapeutic target[1][5]. - It does not encode an alpha-tubulin protein nor contribute to cytoskeletal or cell division functions. - There are no known disease associations, biological roles, or FDA-approved drugs interacting with TUBAP1. - The validated functional tubulin alpha genes with strong biological and clinical significance are *TUBA1A* and *TUBA1B*, which are structurally and functionally distinct from TUBAP1[1][5]. If you are seeking information about *alpha-tubulin proteins* or active alpha-tubulin genes as therapeutic targets (e.g., TUBA1A), please clarify, as those genes are structurally and functionally important and widely studied[1][5].

Other names

TUBAPalpha tubulin (TUBA2) processed pseudogeneTUBAP1