Tubulin beta 3 class III pseudogene 1 (TUBB3P1)

Tubulin beta 3 class III pseudogene 1 (TUBB3P1) is a pseudogene, meaning it shares sequence similarity with the protein-coding gene TUBB3 but contains mutations or deletions that prevent it from encoding the neurally expressed βIII-tubulin protein. While some pseudogenes can play regulatory roles in gene expression, such effects for TUBB3P1 have not been described. Because it cannot produce a functional protein, TUBB3P1 is not considered a drug target, receptor, enzyme, transporter, or biomarker. Information about βIII-tubulin (TUBB3) and its roles in microtubule dynamics, neurogenesis, cancer, and drug resistance is widely available, but these functions do not apply to TUBB3P1, which is a non-coding pseudogene. Key clarification: The name TUBB3P1 can be confused with TUBB3 (the functional gene). Drug targeting, biological function, and disease roles described for βIII-tubulin (TUBB3) are not relevant to TUBB3P1. For drug discovery and therapeutic literature, only the functional TUBB3 (not pseudogene TUBB3P1) is considered actionable.

Other names

Tubulin, beta 3 pseudogene 1Tubulin, beta 3 class III pseudogene 1TUBB3P1