Target intelligence / Profile preview

Tubulin beta 4B class IVb pseudogene 1 (TUBB4BP1)

Target
TUBB4BP1
Molecular classification
Other (Pseudogene)
01

Overview

TUBB4BP1 is a pseudogene located in the human genome that bears high sequence similarity to TUBB4B, a protein-coding beta-tubulin gene. However, unlike TUBB4B, TUBB4BP1 does not encode a functional protein and is generally not transcribed or translated into a product with biological activity. Pseudogenes like TUBB4BP1 are remnants of gene duplication or retrotransposition events and are usually not associated with protein expression, drug interaction, or direct disease roles. The mouse ortholog is named Tubb4b-ps1. This gene should not be considered a valid molecular target in drug discovery, diagnostics, or therapeutic contexts. If you require information on the actual Tubulin beta 4B class IVb (TUBB4B), which is a protein-coding gene involved in microtubule structure and related biological processes (and is a potential disease-associated gene), refer instead to TUBB4B (HGNC 20771).

Other names
TUBB4BP1tubulin beta 4B class IVb pseudogene 1Tubb4b-ps1 (mouse ortholog)TUBB4B pseudogene 1TUBB2C2 (mouse synonym)
02

Mechanism of action

None known or applicable (because it encodes no druggable protein product)

03

Biological functions

Other (No known biological function; pseudogenes generally do not encode active products)
04

Disease associations

Other (No known disease role. The functional TUBB4B gene, not the pseudogene, is implicated in some diseases such as Leber congenital amaurosis with early-onset deafness—not TUBB4BP1.)

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