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Tubulin Polymerization Protein Complex Beta Subunit Family Member 1B Isoform X1 (TUBB1B isoform X1)
- Target
- TUBB1B isoform X1
- Molecular classification
- Tubulin, Cytoskeletal protein
01
Overview
Tubulin polymerization protein complex beta subunit family member 1B isoform X1 is a variant of the beta-tubulin family, a key component of microtubules. Microtubules are essential cytoskeletal structures involved in cell division, intracellular transport, and structural support. As a target for anti-cancer drugs, inhibiting its polymerization disrupts mitosis, leading to cell death.
- Other names
- Beta-tubulin 1B isoform X1
02
Mechanism of action
Inhibition of tubulin polymerization
03
Biological functions
Microtubule formationCell divisionIntracellular transportCiliogenesis
04
Disease associations
CancerNeurodegenerative disease
05
Safety considerations
Drug resistanceOff-target effects of microtubule-targeting agents
06
Interacting drugs
Taxanes
1 more in the full profile.
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