Target intelligence / Profile preview

Tumor-Associated Surface Antigen (TAA)

Target: TAA
Molecular classification: Protein, Glycoprotein

Overview

Tumor-associated surface antigens are overexpressed proteins/glycoproteins found predominantly—but not exclusively—on the surfaces of tumor cells. They play a key role in immune recognition but pose challenges related to specificity and immunogenicity when used as therapeutic targets.

Mechanism of action

Antibody-mediated cell killing, immune cell activation, drug delivery

Biological functions

Immune recognitionCell signalingCell adhesion

Disease associations

Cancer

Safety considerations

Autoimmunity against healthy tissuesOff-target toxicity

Interacting drugs

Monoclonal antibodies

3 more in the full profile.

Biomarkers

Antibody levels against specific TAAs

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