Tumor blood flow modulation

Tumor blood flow modulation" refers to the alteration or regulation of the amount and pattern of blood supplied to tumors. It is not a single molecule, receptor, enzyme, or protein but rather describes a physiological process relevant in oncology. Changes in tumor blood flow can influence how well tumors respond to treatments such as radiotherapy. For example, reductions in tumor blood flow have been shown to predict poorer responses in nasopharyngeal carcinoma patients undergoing radiotherapy[1]. Measurement of TBF can serve as an imaging biomarker for monitoring therapeutic efficacy. However, "tumor blood flow modulation" does not correspond to any specific molecular target suitable for drug binding or direct pharmacological intervention—it is instead an important concept for understanding and optimizing cancer therapy outcomes[1].

Other names

Tumor blood flowTBF modulationtumor perfusion modulation