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Target intelligence / Profile preview
Tumor Cell Surface Marker
- Molecular classification
- Protein, Glycoprotein
01
Overview
Tumor cell surface markers are proteins or glycoproteins expressed on the plasma membrane of tumor cells that can be used to distinguish them from normal cells. They serve as identifiers for different types of tumors and can indicate tumor subtype, stage, metastatic potential, or stemness properties. These markers are used for diagnosis, prognosis, targeted therapy, and research.
02
Mechanism of action
Antibody-mediated cell killing/inhibition; targeted drug delivery
03
Biological functions
Cell identificationCell signalingCell adhesionReceptor bindingDiagnostic markerTherapeutic target
04
Disease associations
CancerMetastasisTumor progression
05
Safety considerations
Off-target toxicityOn-target, off-tumor toxicityImmune responseHeterogeneous expression within tumorsExpression on normal stem/progenitor cells
06
Biomarkers
EpCAMCD44CD133LGR5CA9CA12CLDN1
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