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A tumor lesion in breast cancer refers to a mass or area of abnormal cell growth in the breast tissue resulting from malignant transformation. These lesions are detected through imaging and biopsy, classified histologically and molecularly by features such as hormone receptor status (e.g., ER, PR) or HER2 expression. Each lesion can differ in biological behavior, prognosis, and response to therapy, depending on its molecular subtype and genetic alterations[1][2][3]. The term does not specify any particular molecule, receptor, or protein, but refers generally to the physical manifestation of breast cancer in tissue.
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