Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Tumor Tissue via Localized Beta Emission from Radioisotope Delivery
- Molecular classification
- Radiopharmaceutical
01
Overview
This approach involves the selective destruction of tumor tissue by delivering beta-emitting radioisotopes directly to or near cancer cells. It is not a single molecular entity but a therapeutic strategy where the “target” is defined by selective accumulation within cancerous tissue followed by localized release of cytotoxic beta radiation. Delivery vehicles such as antibodies, peptides, or nanoparticles, guide the radioisotopes, maximizing tumor cell kill while minimizing damage to healthy tissues.
- Other names
- Radioisotope TherapyTargeted Radionuclide TherapyMolecular RadiotherapyPeptide Receptor Radionuclide Therapy (PRRT)Radioimmunotherapy
02
Mechanism of action
Localized delivery of beta-emitting radioisotopes to tumor tissue, resulting in DNA damage and cell death via beta particle emission.
03
Biological functions
Cell death inductionDNA damageTumor growth inhibition
04
Disease associations
Cancer
05
Safety considerations
MyelosuppressionNephrotoxicityOff-target radiation exposureSecondary malignanciesInfusion reactions
06
Interacting drugs
Lutetium Lu 177 dotatate
3 more in the full profile.
07
Biomarkers
PSMA expression (prostate cancer)Somatostatin receptor expression (neuroendocrine tumors)Antigen expression (lymphoma)
Beyond the preview
Go deeper on Tumor Tissue via Localized Beta Emission from Radioisotope Delivery.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Tumor Tissue via Localized Beta Emission from Radioisotope Delivery.