Target intelligence / Profile preview

Tumour cells

Molecular classification
Diverse Cell Types, Epithelial cell, Mesenchymal cell, Neuroendocrine cell, Astrocytic cell
01

Overview

"Tumour cells" refer generically to cells that have acquired mutations enabling malignant transformation, resulting in uncontrolled proliferation, resistance to programmed cell death, potential for invasiveness and metastasis, altered interactions with the microenvironment, and a broad spectrum of genetic and phenotypic heterogeneity. Tumour cells may originate from virtually any tissue and display diverse molecular profiles; therefore, their classification and targeting in therapy are based on more specific molecular features, lineage markers, or tissue of origin rather than the generic designation "tumour cells"[1][2][3][4][5]. If your query seeks information on a *specific target or molecular subtype within tumour cells* (such as "epidermal growth factor receptor" or "PD-1/PD-L1"), please specify, as the category "tumour cells" is too broad and non-specific to map meaningfully to the schema you have outlined.

Other names
Cancer cellNeoplastic cellMalignant cell
02

Biological functions

Cell proliferationEvasion of apoptosisMetastasisAngiogenesisImmune evasionVariable biological processes
03

Disease associations

Cancer

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