Target intelligence / Profile preview

Type II Natural Killer T Cell (Type II NKT Cell)

Target
Type II NKT Cell
Molecular classification
Lymphocyte, Innate-like Lymphocyte, T Cell Subset
01

Overview

Type II natural killer T (type II NKT) cells represent a functionally versatile population within the broader family of CD1d-restricted lymphocytes. With their unique ability to sense diverse lipids through varied receptors—and rapidly shape immune outcomes—they have emerged as important regulators at the interface between innate and adaptive immunity across health and disease contexts.

Other names
Type 2 NKT cellNKTT Cell
02

Mechanism of action

N/A

03

Biological functions

Immune responseCytokine productionImmunoregulationTumor surveillance
04

Disease associations

InfectionAutoimmunityMetabolic diseaseCancerInflammation
05

Safety considerations

Potential to promote inflammation/pathology in certain contextsPotential to contribute to tissue damage in autoimmunity
06

Interacting drugs

CpG oligodeoxynucleotides

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