Tyrosine aminotransferase pseudogene

Tyrosine aminotransferase pseudogene is a **non-functional segment of DNA that resembles the gene encoding the enzyme tyrosine aminotransferase (TAT)**. Pseudogenes are typically generated by duplication or retrotransposition events but lack the regulatory features or sequence integrity to produce functional protein products[1][3]. The pseudogene ENSG00000233583 does not code for an active enzyme and is not implicated in normal physiology or disease, in contrast to the functional TAT gene, which is important in tyrosine metabolism[4][6]. Pseudogenes can occasionally be transcribed at low levels but are generally not of therapeutic or diagnostic interest[1].\n\nSummary of why this is not a therapeutic target: \nThis entry is a **pseudogene**, not a protein-coding gene. It does not yield a functional receptor, enzyme, or other molecule suitable as a drug target. It is often included in gene annotation databases for completeness, but not as a target for intervention or drug development[1][3]. This should not be confused with the functional TAT gene (ENSG00000198650), which encodes the active tyrosine aminotransferase enzyme relevant for metabolism and disease[4][6].

Other names

TAT pseudogenetyrosine transaminase pseudogeneTATP