Target intelligence / Profile preview

Tyrosine-protein kinase TYK1 (TYK1)

Target: TYK1
Molecular classification: Enzyme, Receptor Tyrosine Kinase, Protein Kinase, RTK

Overview

TYK1, also known as leukocyte receptor tyrosine kinase (LTK), is a receptor tyrosine kinase involved in cell growth and differentiation. It phosphorylates target proteins on tyrosine residues, playing a key role in intracellular signaling pathways. While its specific ligand remains unknown, it interacts with several signaling molecules, suggesting its involvement in cell proliferation and survival. Dysregulation of RTKs, including TYK1, is often associated with cancer.

Other names: Leukocyte receptor tyrosine kinaseLTK

Mechanism of action

N/A

Biological functions

Signal transductionCell growthCell differentiationTyrosine phosphorylation

Disease associations

Cancer

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