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Target intelligence / Profile preview
U2 small nuclear RNA auxiliary factor 1-like protein 5 (U2AF1L5)
- Target
- U2AF1L5
- Molecular classification
- Other (Predicted member of splicing factor SR protein family; likely related to RNA binding and pre-mRNA splicing per paralog but itself unclassified)
01
Overview
U2 small nuclear RNA auxiliary factor 1-like protein 5 (U2AF1L5) is a predicted protein-coding gene in the human genome that is homologous to the well-characterized U2AF1 gene, which encodes a key splicing factor involved in the recognition of the 3' splice site during pre-mRNA processing[1][5]. U2AF1L5 itself is not functionally characterized, and there is no published evidence supporting its involvement in splicing, disease pathology, or therapeutic targeting. Most information available in published resources refers to its paralog U2AF1, which plays a central role in RNA splicing, implicates in various cancers, and interacts with other splicing factors. Because U2AF1L5 is a *predicted* gene (lacking direct experimental evidence), it should not be referenced as a true protein target for therapeutic or diagnostic purposes unless further research clarifies its function.
- Other names
- U2AF1L5U2 small nuclear RNA auxiliary factor 1-like protein 5Splicing factor U2AF 35 kDa subunit-like proteinLOC102724594
02
Mechanism of action
None reported
03
Biological functions
Other (No experimentally validated biological function for U2AF1L5; presumed to be involved in RNA splicing by homology with U2AF1[1][5])
04
Disease associations
Other (No known disease associations; U2AF1 mutations are linked to cancer and blood disorders[1][5], but this is not established for U2AF1L5)
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