U3 small nucleolar RNA-associated protein 18 homolog, pseudogene

U3 small nucleolar RNA-associated protein 18 homolog, pseudogene (also known as ENSG00000267293 or LOC100422497) is annotated as a **pseudogene** in the human genome[3]. Pseudogenes are genomic DNA sequences similar to normal genes but are non-functional; they typically do not encode functional proteins and do not serve as drug targets, disease drivers, or biomarkers. This pseudogene appears related by sequence to the functional gene UTP18, which encodes a ribosome biogenesis factor, but there is no evidence that the pseudogene itself is transcribed or translated, nor that it has a direct biological or disease role[3][7]. Additional context: This entry should not be used as a therapeutic target, and there is no evidence that it functions as a receptor, enzyme, transporter, or other classic drug target. The confusion may arise from similarity to the functional UTP18 gene[5][7], but ENSG00000267293 specifically represents a non-functional pseudogene copy. Summary of issues: - This is a pseudogene, not an active molecular target[3]. - Not suitable for therapeutic targeting or research as a biomarker or therapy mechanism. - No known protein product, function, disease link, or drug interaction. If you are seeking information on the functional, protein-coding form, refer instead to the UTP18 gene (U3 small nucleolar RNA-associated protein 18 homolog, human, functional gene)[5][7].

Other names

LOC100422497ENSG00000267293