U6 small nuclear RNA 387, pseudogene (RNU6-387P)

RNU6-387P is a pseudogene of the U6 small nuclear RNA (snRNA) gene. U6 snRNA is a highly conserved, non-coding RNA that is essential for the catalytic steps of pre-mRNA splicing in eukaryotic spliceosomes, acting as part of the core machinery that removes introns from pre-mRNA within the nucleus[1][3]. The "pseudogene" designation means RNU6-387P resembles the functional U6 snRNA gene but *does not* produce the canonical snRNA product, due to disabling mutations or loss of regulatory sequences. Thousands of such pseudogenes exist in the human genome[2]; some are transcriptionally active and may generate non-coding RNAs with potential regulatory functions (such as miRNA sponging or epigenetic regulation), but there is no evidence that RNU6-387P has a specific or characterized functional/disease role[2][5]. It is *not* considered a therapeutic target, receptor, or enzyme. Summary: - RNU6-387P is not a therapeutic target, but rather a non-functional pseudogene related to the splicing-factor U6 snRNA gene. - It does not encode protein, has no described drug interactions, and no direct disease associations[1][2][3][5]. - It may have regulatory roles common to some pseudogenes, but no target- or receptor-like function.

Other names

RNA, U6 small nuclear 387, pseudogeneRNU6-387PU6 snRNA pseudogene 387