U6 small nuclear RNA 7 (RNU6-7)

U6 small nuclear RNA 7 is one of multiple highly conserved, non-coding small nuclear RNAs that form essential components of the spliceosome—a complex responsible for catalyzing the excision of introns from precursor messenger RNA in eukaryotic nuclei[1][2][3][5]. U6 snRNAs serve as the catalytic core of the spliceosome, directly participating in splicing chemistry and structural rearrangements essential for pre-mRNA processing. Although there are multiple genes and pseudogenes encoding U6 RNAs in the genome (RNU6-1, RNU6-7, etc.), they share near-identical functions. U6 snRNAs are not typical therapeutic targets, but are essential for cell viability and fundamental gene expression. The U6 snRNA gene family is highly conserved, reflecting its critical evolutionary role[1][3][5]. If seeking a drug target or biomarker, U6 snRNA or RNU6-7 is not appropriate as it functions as a ubiquitous, essential RNA for splicing rather than as a modifiable enzyme, receptor, or signaling molecule.

Other names

U6-7RNU6-7U6 small nuclear RNA 7