U6 snRNA-associated Sm-like protein LSm6 (LSM6)

U6 snRNA-associated Sm-like protein LSm6 is a protein encoded by the human LSM6 gene and functions as a component of the LSm protein complexes involved in RNA processing, particularly pre-mRNA splicing. LSm6 belongs to the Sm-like protein family, which shares sequence homology with the classical Sm protein family and contains a characteristic Sm sequence motif composed of two regions separated by a loop. LSm6 is a subunit of the tri-snRNP particle essential for spliceosome assembly, a critical step in the maturation of pre-mRNA transcripts. It is primarily localized in the cytoplasm and acts upstream in the mRNA catabolic process. There is no current evidence implicating LSm6 directly as a therapeutic target or biomarker, nor are there associated safety concerns or interacting drugs described in the literature.

Other names

LSM6LSM6 homologYDR378CU6 small nuclear RNA and mRNA degradation associatedSm protein FU6 snRNA-associated Sm-like protein LSm6

Not applicable (no drugs have been reported to target LSm6)