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UBA5 pseudogene 1 (UBA5P1) is a genetic sequence on human chromosome 1 that shares high sequence similarity with the UBA5 gene, which encodes the ubiquitin-like modifier-activating enzyme 5—an E1 enzyme critical for activating UFM1 in the post-translational modification pathway known as UFMylation. UBA5P1, however, is a pseudogene and does not encode a functional protein product[4]. Therefore, it lacks a defined biological or disease role, is not a drug target, and is not associated with any known molecular interactions or therapeutic applications. Important clarification: If you are interested in the enzyme involved in UFMylation and disease, you should reference the functional gene Ubiquitin-like modifier-activating enzyme 5 (UBA5), not UBA5P1[1][2][3][4][5][6]. The true target is UBA5, not its pseudogene. Summary: UBA5P1 is not a therapeutic or molecular target; it is a retired/disrupted gene segment with no established function or clinical relevance[4]. For target information, use UBA5 (not UBA5P1).
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