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Target intelligence / Profile preview
UBE2D3 antisense RNA 1 (UBE2D3-AS1)
- Target
- UBE2D3-AS1
- Molecular classification
- Long non-coding RNA, antisense RNA
01
Overview
UBE2D3 antisense RNA 1 (UBE2D3-AS1) is a natural antisense long non-coding RNA transcribed from the opposite strand of the UBE2D3 gene[2][5]. Like other antisense RNAs, it may have regulatory effects on the expression of its sense partner gene, but its specific functional consequences, biological activities, and clinical significance remain poorly defined[2][6]. UBE2D3-AS1 has been detected in genomic studies and shown to be upregulated in some cancers, but is not currently recognized as a functional protein, conventional drug target, or clinically actionable biomarker[2][6].
- Other names
- UBE2D3-AS1UBE2D3 antisense RNA 1
02
Mechanism of action
Not applicable or unknown; no drugs target UBE2D3-AS1 directly.
03
Biological functions
Not specifically characterized; generally, antisense RNAs are implicated in regulation of their sense counterpart gene (e.g., UBE2D3), but the distinct functional role of UBE2D3-AS1 is not reported in current research
04
Disease associations
UBE2D3-AS1 has been found upregulated in certain cancers, such as osteosarcoma, suggesting a possible association with cancerSpecific mechanistic or clinical disease relationships remain unclear
05
Safety considerations
Not applicable, as it is not a target for any therapeutic modality at present
06
Interacting drugs
No described drugs are known to directly interact with UBE2D3-AS1
07
Biomarkers
Not established as a clinical biomarker; its upregulation in some cancer types is reported but not clinically validated
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