UBE2L3 pseudogene 2 (UBE2L3P2)

UBE2L3 pseudogene 2 (UBE2L3P2) is a **pseudogene** related to the UBE2L3 gene. Unlike the protein-coding UBE2L3 gene, which encodes ubiquitin-conjugating enzyme E2 L3 involved in ubiquitination and cellular processes such as protein degradation and immune regulation[1][2][3][5], UBE2L3P2 **does not produce a functional protein, has no known biological function, and is not a therapeutic target**. It derives its sequence from the ancestral UBE2L3 gene but is formally classified as a pseudogene and is not associated with validated disease roles, drug interactions, or clinical biomarker utility[3][1]. **Additional clarification:** - There is no evidence from any source that the pseudogene UBE2L3P2 serves as a receptor, enzyme, transporter, or in any other role relevant for drug targeting, diagnosis, or biomarker development. - The true therapeutic target, for various diseases, is the functional gene UBE2L3 (ubiquitin-conjugating enzyme E2 L3, abbreviation UBCH7), not its pseudogenes[1][2][5]. **Summary of correctness:** - The entry "UBE2L3 pseudogene 2" is **incorrect or inappropriate as a therapeutic target**; all known significant biomedical roles belong to the functional UBE2L3 gene, not the pseudogene. If a therapeutic target is intended, the correct entity is "Ubiquitin-conjugating enzyme E2 L3 (UBE2L3 / UBCH7)"[1][2][5].

Other names

UBE2L3P2

None (not targeted by drugs)