UBE2V1 pseudogene 14 (UBE2V1P14)

UBE2V1 pseudogene 14 (UBE2V1P14) is a genomic locus annotated as a pseudogene on chromosome 20. It shares sequence similarity with the protein-coding UBE2V1 gene, but it contains mutations—such as stop codons or frameshifts—that prevent expression of a functional protein[5]. Pseudogenes like UBE2V1P14 are usually remnants of gene duplication or retrotransposition events and generally lack known biological or disease functions. UBE2V1P14 is not a receptor, enzyme, transporter, transcription factor, or any other recognized drug target. If you intended to refer to the functional gene or protein relevant in ubiquitination (UBE2V1), you should use "Ubiquitin-conjugating enzyme E2 variant 1" (abbreviation: UBE2V1), which is a real protein-coding gene involved in various cellular processes, including K63-linked ubiquitination, DNA repair, and protein aggregation[1][2][3][4][6]. UBE2V1P14, however, is not suitable for analysis as a therapeutic target due to its noncoding nature[5].

Other names

UBE2V1P14UBE2V1 pseudogene 14