UBE2V1 pseudogene 5 (UBE2V1P5)

UBE2V1P5, or "UBE2V1 pseudogene 5", is a pseudogene related to the canonical UBE2V1 gene, which encodes ubiquitin-conjugating enzyme E2 variant 1. UBE2V1P5 does not encode a functional protein and is not recognized as a therapeutic target. UBE2V1P5 (UBE2V1 pseudogene 5) is a human pseudogene related to the UBE2V1 family located on chromosome 20[3]. As a pseudogene, UBE2V1P5 contains sequence similarity to the active UBE2V1 gene but does not encode a functional protein and has no enzymatic or structural function in the cell. It is not involved in known disease pathways, does not serve as a clinical biomarker or drug target, and does not play a direct role in biological processes or disease[3]. It is distinct from the functional UBE2V1 gene, which catalyzes Lys-63-linked polyubiquitination and has established roles in immune response, DNA repair, and cell signaling[1][2][5][8]. Note: If your intent is to refer to the druggable E2 enzyme protein, you should instead use "Ubiquitin-conjugating enzyme E2 variant 1" (UBE2V1), not UBE2V1P5, which is a non-functional pseudogene[1][2][8].

Other names

ubiquitin conjugating enzyme E2 V1 pseudogene 5ubiquitin conjugating enzyme E2 variant 1 pseudogene 5ubiquitin-conjugating enzyme E2 variant 2 pseudogene