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This designation refers to a nonfunctional, noncoding pseudogene that resembles the functional ubiquitinol-cytochrome c reductase hinge protein gene (UQCRH). While annotated as a pseudogene, it retains an open reading frame, but there is no reliable evidence that it encodes a protein product. Pseudogenes like this typically do not have biological functions as proteins or roles in disease, and are not therapeutic targets. The parental gene, UQCRH, is a nuclear-encoded component of mitochondrial Complex III important for oxidative phosphorylation, but the pseudogene version is essentially a genomic remnant lacking clear function.
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