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Ubiquitin carboxyl-terminal esterase L1 pseudogene
- Molecular classification
- Pseudogene
01
Overview
Ubiquitin carboxyl-terminal esterase L1 pseudogene (ENSG00000254411; LOC100128210) is a non-functional genomic locus related to the UCHL1 gene, which encodes a deubiquitinating enzyme involved in proteostasis and is expressed in neurons. Pseudogenes such as ENSG00000254411 do not encode functional proteins, are not involved in canonical biological processes, and are not recognized therapeutic targets. All known functional, disease-related, or therapeutic roles in the literature pertain to the protein-coding UCHL1 gene, not to this pseudogene. Identification of ENSG00000254411 as a target for pharmacological intervention is incorrect; for therapeutic, mechanistic, or biomarker context, the corresponding protein-coding gene (UCHL1) should be referenced instead[2][3][5].
- Other names
- LOC100128210Ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) pseudogeneENSG00000254411
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