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Ubiquitin-like with PHD and ring finger domains 1 pseudogene

Molecular classification
Other (Pseudogene)
01

Overview

Ubiquitin-like with PHD and ring finger domains 1 pseudogene (ENSG00000256663) is a DNA sequence in the human genome that bears high similarity to the functional UHRF1 gene, but it has lost the ability to code for a protein due to the accumulation of disabling mutations[1][5]. As a **pseudogene**, it does not produce functional UHRF1 protein and is not known to have a direct biological or therapeutic function. While some pseudogenes can exert regulatory effects at the RNA level, most—including this locus—are not considered classical drug targets. The primary scientific interest in such pseudogenes relates to their evolutionary origin, possible subtle regulatory roles, and their potential impact on genetic testing accuracy[3][5].

Other names
GC12P020706GC12P020552
02

Biological functions

Some pseudogenes have regulatory roles in gene expression via RNA-mediated mechanisms[3][4], but specific functions for this pseudogene are unknown.Generally, pseudogenes may act as miRNA decoys or produce noncoding RNAs with possible regulatory activity, but most have no well-characterized function[3][4].
03

Disease associations

Other (For most pseudogenes, specific disease associations are not established, unless evidence from regulatory function exists, which is not the case here.)

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