Ubiquitin specific peptidase 10 pseudogene

The "ubiquitin specific peptidase 10 pseudogene" is a non-functional DNA sequence in the human genome that resembles, but does not produce, the active enzyme known as ubiquitin specific peptidase 10 (USP10)[4][2]. Pseudogenes such as this typically arise due to gene duplication or retrotransposition, acquiring mutations that prevent proper transcription or translation, and are generally considered "junk DNA" with no protein-coding function[4][2]. They are not considered valid drug or biomarker targets, and do not participate in biological or pathological signaling pathways relevant to therapeutics[4][2]. While the functional gene USP10 is an enzyme involved in deubiquitination and implicated in various cellular processes and diseases, the pseudogene version does not encode any functional protein, has no validated biological function, and is not therapeutically actionable[1][3][5][4]. The use of "ENSG00000257175" or "ubiquitin specific peptidase 10 pseudogene" as a therapeutic target is incorrect, and no structured information related to drug interactions, biomarkers, or clinical context applies to this pseudogene[4].

Other names

USP10 pseudogeneubiquitin specific protease 10 pseudogene