Ubiquitin specific peptidase 17 like family member 16, pseudogene (USP17L16P)

**Ubiquitin specific peptidase 17 like family member 16, pseudogene (USP17L16P)** is classified as a pseudogene located on chromosome 4p16.1[3]. As a pseudogene, it is a non-functional segment of DNA similar to a protein-coding gene but contains mutations or deletions that prevent expression of a functional protein[5]. USP17L16P is part of a cluster of USP17-related pseudogenes, all derived from the parent gene family that encodes deubiquitinating enzymes involved in controlling protein degradation and cellular signaling. However, USP17L16P itself does not encode an active enzyme and is not known to have a biological or disease-related role, nor is it considered a therapeutic target[3][5][6]. **Essential context and supporting details:** - USP17L16P is listed in the HUGO Gene Nomenclature Committee with locus type "pseudogene," indicating that it is not a protein-coding gene[3]. - Pseudogenes like USP17L16P originate from duplication or retrotransposition events involving functional genes[5]. - Unlike its functional relatives (such as other USP17 genes), USP17L16P lacks functional gene product due to detrimental alterations. - There is no current evidence that USP17L16P is expressed or plays any regulatory or structural role in cells, nor is it associated with any disease phenotype or drug sensitivity. - There are no known aliases, common abbreviations, interacting drugs, mechanisms of action, disease roles, or biomarkers attributed to this pseudogene. - The presence of "pseudogene" in the name, and confirmation by multiple authoritative sources, indicates this is not a valid therapeutic target[3][6].