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Ubiquitin specific peptidase 17 pseudogene
- Molecular classification
- Other (Pseudogene)
01
Overview
Ubiquitin specific peptidase 17 pseudogene (ENSG00000255211, LOC392187) is a nonfunctional DNA segment related to the USP17 gene family, lacking protein-coding ability due to disabling mutations[4]. While pseudogenes were traditionally considered "junk DNA," recent research reveals that some pseudogenes participate in the regulation of gene expression at the RNA level, for example by acting as microRNA decoys or sources of small interfering RNAs, with potential roles in cancer biology and other regulatory processes[2]. However, this specific pseudogene is not recognized as a therapeutic target and does not encode a functional protein[4].
- Other names
- LOC392187ENSG00000255211
02
Biological functions
Potential regulatory functions at the RNA level, including possible involvement in RNA interference and miRNA decoy activity[2]. Not protein-coding nor enzymatic.
03
Disease associations
Other (Some pseudogenes have been implicated in cancer and may act as regulators of tumor suppressors or oncogenes, but specific disease roles for this pseudogene are unconfirmed[2]).
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