Ubiquitin specific peptidase 22 pseudogene

Ubiquitin specific peptidase 22 pseudogene is a nonfunctional genomic DNA segment derived from the functional USP22 gene. Like most pseudogenes, it shares sequence similarity with USP22 but contains disabling mutations, preventing the production of a functional protein product. Pseudogenes such as ENSG00000234406 are typically considered genomic "junk DNA," though some can, in rare instances, acquire regulatory roles; however, there is no current evidence this pseudogene has any biological function or clinical significance[2][4]. Key clarification: The validated therapeutic target is the protein-coding USP22 gene, not this pseudogene. Pseudogenes can sometimes complicate genetic analysis due to sequence similarity but are not considered as drug targets[2].

Other names

USP22PUSP22P1Ubiquitin specific peptidase 22 pseudogene