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Ubiquitin specific peptidase 41 pseudogene (USP41P)

Target
USP41P
Molecular classification
Other (Pseudogene)
01

Overview

Ubiquitin specific peptidase 41 pseudogene (USP41P, ENSG00000266470) is a processed pseudogene in the human genome arising from the parental gene encoding a deubiquitinating enzyme. Pseudogenes are typically nonfunctional DNA sequences derived from once-functional genes; they frequently contain frameshift mutations or stop codons, preventing expression of functional protein. USP41P is annotated as a pseudogene, lacks protein-coding capacity, and is not considered a therapeutic target or functionally relevant gene in disease or normal physiology[5][2][4]. Notes: - USP41 (not the pseudogene) belongs to the family of ubiquitin-specific peptidases, which are involved in the removal of ubiquitin from substrates and are potentially druggable enzymes[3]. However, the pseudogene forms (such as USP41P/USP41 pseudogene) are not known to produce any active protein or contribute functionally to the ubiquitin-proteasome system. - As a pseudogene, USP41P does not participate directly in known molecular pathways and is not subject to pharmacological intervention. If you require information on the functional form (the full protein-coding "Ubiquitin specific peptidase 41" or USP41), or details on other USP family deubiquitinases and their roles as drug targets, please clarify.

Other names
USP41PUSP41 pseudogeneUbiquitin specific peptidase 41, pseudogene

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