Ubiquitin specific peptidase 9, Y-linked pseudogene 28 (USP9YP28)

USP9YP28 stands for ubiquitin specific peptidase 9, Y-linked pseudogene 28. It is a Y chromosome–encoded pseudogene related by sequence to the functional gene USP9Y, which encodes a deubiquitinating enzyme important for male germ cell development. However, USP9YP28 itself is not believed to encode a protein product, and there is no evidence for direct biological function or disease association. Pseudogenes like USP9YP28 are generally regarded as remnants of duplicated or retrotransposed genes that have lost protein-coding capacity; sometimes, pseudogenes may have regulatory roles (e.g., via lncRNAs), but there is no published evidence for such a role in USP9YP28. It is catalogued primarily in genomic databases and is not considered a drug target or therapeutic entity. USP9YP28 is a non-protein-coding pseudogene, not a validated drug target, and is not involved in recognized disease pathways or therapeutics. Its name and inclusion in target lists may result from confusion with the functional, protein-coding gene USP9Y, which does play a demonstrated role in male fertility.

Other names

ubiquitin specific peptidase 9, Y-linked pseudogene 28USP9YP28

None identified. No therapeutic interventions or relevant molecular modulators are known for this pseudogene.