Ubiquitin-specific protease pseudogene

ENSG00000235778 refers to a ubiquitin-specific protease pseudogene, also known as the ubiquitin carboxyl-terminal hydrolase 17-like pseudogene (LOC402329)[3]. Pseudogenes are genomic sequences related to protein-coding genes but are non-functional due to mutations or genetic rearrangements. Unlike their functional protein-coding relatives—such as the ubiquitin-specific protease (USP) family, which are involved in protein regulation via the ubiquitin-proteasome system and play key roles in processes like cell cycle regulation, apoptosis, and cancer—this pseudogene does not produce an active enzyme and does not participate in these pathways[3][2]. There are no known roles for this pseudogene in disease, no interacting drugs, and no mechanism of action or safety concerns associated with it. Its primary distinction is that, while it shares sequence similarity with functional USP genes, it remains non-functional and is not considered a therapeutic target.

Other names

ubiquitin carboxyl-terminal hydrolase 17-like pseudogeneLOC402329

None (not druggable, no mechanism of action)