Target intelligence / Profile preview

Ultraviolet B radiation (UVB)

Target: UVB
Molecular classification: Electromagnetic radiation

Overview

Ultraviolet B radiation is a highly energetic portion of solar ultraviolet light with wavelengths between 280 and 315 nm that primarily targets epidermal structures—especially DNA—causing acute effects like sunburn as well as chronic risks including various forms of skin cancer. It also plays an essential physiological role in vitamin D synthesis but must be carefully balanced due to its mutagenic potential at even low exposures.

Biological functions

Vitamin D synthesisDNA damageImmunosuppressionMelanin productionEpidermal thickening

Disease associations

Skin cancer (melanoma)Skin cancer (non-melanoma)SunburnPhotoagingImmunodeficiency

Safety considerations

Increased risk of skin cancerSunburnPhotoagingImmunosuppression

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