UNC93B6

UNC93B6 refers to an uncharacterized or misidentified gene/pseudogene and does not correspond to a known therapeutic target. The primary UNC93 family member of biological and therapeutic significance in humans is "Unc-93 homolog B1 (UNC93B1)", which is a multi-pass membrane protein critical for trafficking nucleic-acid–sensing Toll-like receptors (TLR3, TLR7, TLR8, TLR9) from the endoplasmic reticulum to endolysosomes, and plays a role in innate immune signaling, infection susceptibility, and autoimmunity[1][5][3]. However, UNC93B6 is annotated as a pseudogene and does not encode a functional protein, nor is it a receptor, enzyme, transporter, or an established therapeutic target[1]. UNC93B6 is likely a **pseudogene** and not a therapeutically relevant molecule. The functional molecule in this family is **UNC93B1**. No drugs, mechanisms of action, or known disease roles are associated with UNC93B6[1].

Other names

UNC93 homolog B6 (pseudogene)