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Target intelligence / Profile preview
FLJ42393 (also known as uncharacterized LOC401105 or AVPC1948) is a putative gene located on human chromosome 3q27.3–q28. Its transcript is designated as NR_024413.1, but the protein product is currently uncharacterized, and there are no validated functional or structural studies confirming its role as a receptor, enzyme, or other canonical molecular target. Predictions based on text-mining and gene ontology insertion hint at possible roles in regulation of transcription and nucleic acid binding; it is annotated as a potential transcription regulator. There is some evidence of its downregulation in certain cell lines (e.g., HCT116 p53 wildtype), but there is no established evidence supporting its function in disease, nor proof it is a validated therapeutic target. This gene does not appear in drug-target databases, and there are no reports of known drugs interacting with it.
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